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Published in 2022 at "Human Brain Mapping"
DOI: 10.1002/hbm.25774
Abstract: This study sought to identify a reference tissue‐based quantification approach for improving the statistical power in detecting changes in brain glucose metabolism, amyloid, and tau deposition in Alzheimer's disease studies. A total of 794, 906,…
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Keywords:
reference;
disease;
florbetapir 18f;
18f florbetapir ... See more keywords
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Published in 2019 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-019-04533-y
Abstract: We evaluated myelin changes throughout the central nervous system in Multiple Sclerosis (MS) patients by using hybrid [18F]florbetapir PET-MR imaging. We included 18 relapsing-remitting MS patients and 12 healthy controls. Each subject performed a hybrid…
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Keywords:
multiple sclerosis;
pet imaging;
18f florbetapir;
florbetapir pet ... See more keywords
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Published in 2019 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-019-04627-7
Abstract: The clinical diagnosis of pulmonary involvement in individuals with systemic AL amyloidosis remains challenging. [18F]florbetapir imaging has previously identified AL amyloid deposits in the heart and extra-cardiac organs. The aim of this study is to…
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Keywords:
18f florbetapir;
amyloidosis;
systemic amyloidosis;
quantitative 18f ... See more keywords
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Published in 2020 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-020-05006-3
Abstract: Visual reading of 18F-florbetapir positron emission tomography (PET) scans is used in the diagnostic process of patients with cognitive disorders for assessment of amyloid-ß (Aß) depositions. However, this can be time-consuming, and difficult in case…
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Keywords:
18f florbetapir;
convolutional neural;
positive 18f;
neural network ... See more keywords
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Published in 2017 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2017.03.003
Abstract: BACKGROUND/PURPOSE To determine whether dual-phase 18F-florbetapir positron emission tomography imaging with perfusion-like and amyloid deposition information can distinguish among primary progressive aphasia (PPA), Alzheimer's disease (AD), and healthy controls (HCs). METHODS Patients diagnosed with PPA,…
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Keywords:
phase;
phase 18f;
18f florbetapir;
ppa patients ... See more keywords
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Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0177924
Abstract: Parkinson disease patients develop clinically significant cognitive impairment at variable times over their disease course, which is often preceded by milder deficits in memory, visuo-spatial, and executive domains. The significance of amyloid-β accumulation to these…
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Keywords:
cognitive impairment;
18f florbetapir;
performance;
parkinson disease ... See more keywords