Prevalence of hypoxia and correlation with glycolytic metabolism and angiogenic biomarkers in metastatic colorectal carcinoma
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-020-05074-5
Abstract: Hypoxia is associated with aggressive tumour behaviour and can influence response to systemic therapy and radiotherapy. The prevalence of hypoxia in metastatic colorectal cancer is poorly understood, and the relationship of hypoxia to patient outcomes… read more here.
Keywords: metastatic colorectal; glycolytic metabolism; colorectal cancer; 18f fmiso ... See more keywords
[18F]FMISO PET/CT imaging of hypoxia as a non-invasive biomarker of disease progression and therapy efficacy in a preclinical model of pulmonary fibrosis: comparison with the [18F]FDG PET/CT approach
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-021-05209-2
Abstract: Idiopathic pulmonary fibrosis (IPF) is a progressive disease with poor outcome and limited therapeutic options. Imaging of IPF is limited to high-resolution computed tomography (HRCT) which is often not sufficient for a definite diagnosis and… read more here.
Keywords: pet; fibrosis; disease; 18f fmiso ... See more keywords
Quantification of Tumor Hypoxic Fractions Using Positron Emission Tomography with [18F]Fluoromisonidazole ([18F]FMISO) Kinetic Analysis and Invasive Oxygen Measurements
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-017-1083-9
Abstract: PurposeThe purpose of this study is to use dynamic [18F]fluoromisonidazole ([18F]FMISO) positron emission tomography (PET) to compare estimates of tumor hypoxic fractions (HFs) derived by tracer kinetic modeling, tissue-to-blood ratios (TBR), and independent oxygen (pO2)… read more here.
Keywords: 18f fluoromisonidazole; fluoromisonidazole 18f; 18f fmiso; positron emission ... See more keywords
Comparison of Hypermetabolic and Hypoxic Volumes Delineated on [18F]FDG and [18F]Fluoromisonidazole PET/CT in Non-small-cell Lung Cancer Patients
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-019-01422-6
Abstract: The high rates of failure in the radiotherapy target volume suggest that patients with stage II or III non-small-cell lung cancer (NSCLC) should receive an increased total dose of radiotherapy. 2-Deoxy-2-[18F]fluoro-d-glucose ([18F]FDG) and [18F]fluoromisonidazole ([18F]FMISO)… read more here.
Keywords: 18f fmiso; fdg 18f; 18f fdg; lung cancer ... See more keywords
Accumulation of hypoxia imaging probe “18F-FMISO” in macrophages depends on macrophage polarization in addition to hypoxic state
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Nuclear Medicine"
DOI: 10.1007/s12149-019-01332-1
Abstract: ObjectiveMacrophages play an essential role in immune response, and are closely related to the progression of diseases such as cancer and atherosclerosis. Macrophages polarize to M1 or M2 type, which is related to the environmental… read more here.
Keywords: state; accumulation; polarization; 18f fmiso ... See more keywords
Geometric analysis of loco-regional recurrences in relation to pre-treatment hypoxia in patients with head and neck cancer
Sign Up to like & getrecommendations! Published in 2017 at "Acta Oncologica"
DOI: 10.1080/0284186x.2017.1372626
Abstract: Abstract Introduction: A previous pattern-of-failure study has suggested that up to 50% of the loco-regional failures (LRF) in head and neck squamous cell carcinoma (HNSCC) occur outside the initial hypoxic volume determined by [18F]-fluoromisonidazole-PET ([18F]-FMISO-PET).… read more here.
Keywords: pet; analysis; loco regional; 18f fmiso ... See more keywords
Regional 18F-fluoromisonidazole PET images generated from multiple advanced MR images using neural networks in glioblastoma
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000029572
Abstract: Generated 18F-fluoromisonidazole (18F-FMISO) positron emission tomography (PET) images for glioblastoma are highly sought after because 18F-FMISO can be radioactive, and the imaging procedure is not easy. This study aimed to explore the feasibility of using… read more here.
Keywords: 18f fmiso; regional 18f; advanced images; fmiso images ... See more keywords
18F-FMISO PET of an Intracranial Tuberculoma: A Great Mimicker.
Sign Up to like & getrecommendations! Published in 2022 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000004471
Abstract: ABSTRACT Solitary intracranial tuberculomas are rare and frequently misdiagnosed as brain tumors. We report a case of intracranial tuberculous granuloma mimicking a high-grade glioma with avid uptake on 18F-fluoromisonidazole PET/CT. It has been believed that… read more here.
Keywords: fmiso pet; great mimicker; pet intracranial; 18f fmiso ... See more keywords
Hypoxia Imaging and Biological Evaluation of the Radiosensitizing Effect of Oleanolic Acid
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DOI: 10.1155/2018/2694679
Abstract: Background and Purpose The aim of this study was to evaluate the radiosensitizing effect of oleanolic acid (OA) on C6 rat glioma and the changes in tumor biology during radiosensitization therapy on 18F-fluoromisonidazole (18F-FMISO) positron… read more here.
Keywords: effect oleanolic; 18f fmiso; biology; radiosensitizing effect ... See more keywords
18F-Fluoromisonidazole in tumor hypoxia imaging
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.21662
Abstract: Hypoxia is a common feature of solid tumors that is closely associated with radiotherapy and chemotherapy resistance, metastasis and tumors prognosis. Thus, it is important to assess hypoxia in tumors for estimating prognosis and selecting… read more here.
Keywords: 18f fluoromisonidazole; 18f fmiso; tumor hypoxia; fmiso pet ... See more keywords
Dual-Tracer Assessment of Dynamic Changes in Reoxygenation and Proliferation Decrease During Fractionated Radiotherapy in Murine Tumors
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2020.01046
Abstract: Objective: The present work aimed to assess reoxygenation and tumor inhibition during fractionated radiotherapy (FRT) in murine tumors using 18F-fluoromisonidazole (18F-FMISO) and 18F-fluorothymidine (18F-FLT) based micro positron emission tomography/computed tomography (PET/CT). Materials and Methods: A… read more here.
Keywords: inter frt; pet; frt; 18f fmiso ... See more keywords