Radiotracer stereochemistry affects substrate affinity and kinetics for improved imaging of system xC- in tumors
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DOI: 10.7150/thno.63237
Abstract: Amino acid utilization is perturbed in cancer cells, which rewire their metabolism to support cell survival and proliferation. This metabolic reprogramming can be exploited for diagnostic purposes through positron emission tomography imaging of fluorine-18 labeled… read more here.
Keywords: system; 18f frpg; 18f fspg; stereochemistry ... See more keywords