Identification and Preclinical Development of a 2,5,6-Trisubstituted Fluorinated Pyridine Derivative as a Radioligand for the Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors.
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DOI: 10.1021/acs.jmedchem.0c00778
Abstract: Despite the broad implications of the cannabinoid type 2 receptor (CB2) in neuroinflammatory processes, a suitable CB2-targeted probe is currently lacking in clinical routine. As part of our medicinal chemistry program, we have recently identified… read more here.
Keywords: cannabinoid type; pyridine; chemistry; cb2 ... See more keywords