Synaptic Density Reductions in MSA: A Potential Biomarker Identified Through [18F]SynVesT‐1 PET Imaging
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DOI: 10.1002/ana.27179
Abstract: The objective of this study was to delineate synaptic density alterations in multiple system atrophy (MSA) and explore its potential role as a biomarker for MSA diagnosis and disease severity monitoring using [18F]SynVesT‐1 positron emission… read more here.
Keywords: synaptic density; pet; 18f synvest; density reductions ... See more keywords
Detection of changes in synaptic density in amyotrophic lateral sclerosis patients using 18F‐SynVesT‐1 positron emission tomography
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DOI: 10.1111/ene.15451
Abstract: Synaptic loss is well established as the major correlate of characteristic and consistent pathology in amyotrophic lateral sclerosis (ALS). We aimed to assess the possible discriminant diagnostic value of 18F‐SynVesT‐1 positron emission tomography (PET) as… read more here.
Keywords: positron emission; 18f synvest; pathology; lateral sclerosis ... See more keywords
Imaging Synaptic Density in Aging and Alzheimer Disease with [18F]SynVesT-1
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DOI: 10.2967/jnumed.124.269005
Abstract: Visual Abstract Synaptic density imaging with PET is a relatively new approach to monitoring synaptic injury in neurodegenerative diseases. However, there are remaining technical and clinical questions, including questions on reference region selection and on… read more here.
Keywords: alzheimer disease; whole brain; synaptic density; density ... See more keywords