Identification of [18F]TRACK, a Fluorine-18-Labeled Tropomyosin Receptor Kinase (Trk) Inhibitor for PET Imaging.
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DOI: 10.1021/acs.jmedchem.7b01607
Abstract: Changes in expression and dysfunctional signaling of TrkA/B/C receptors and oncogenic Trk fusion proteins are found in neurological diseases and cancers. Here, we describe the development of a first 18F-labeled optimized lead suitable for in… read more here.
Keywords: trk; fluorine labeled; identification 18f; 18f track ... See more keywords