Radiosynthesis and biological evaluation of [18F]Triacoxib: A new radiotracer for PET imaging of COX-2.
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DOI: 10.1021/acs.molpharmaceut.9b00986
Abstract: Inducible isozyme cyclooxygenase-2 (COX-2) is upregulated under acute and chronic inflammatory conditions, including cancer, wherein it promotes angiogenesis, tissue invasion, and resistance to apoptosis. Due to its high expression in various cancers, COX-2 has become… read more here.
Keywords: radiotracer; pet imaging; chemistry; 18f triacoxib ... See more keywords