Efficient Screening of Target‐Specific Selected Compounds in Mixtures by 19F NMR Binding Assay with Predicted 19F NMR Chemical Shifts
Sign Up to like & getrecommendations! Published in 2022 at "ChemMedChem"
DOI: 10.1002/cmdc.202200163
Abstract: Ligand‐based 19F NMR screening is a highly effective and well‐established hit‐finding approach. The high sensitivity to protein binding makes it particularly suitable for fragment screening. Different criteria can be considered for generating fluorinated fragment libraries.… read more here.
Keywords: 19f nmr; chemical shifts; nmr chemical; predicted 19f ... See more keywords
19F NMR Spectroscopy for the Analysis of DNA G-Quadruplex Structures Using 19F-Labeled Nucleobase.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9666-7_26
Abstract: G-quadruplex structures have been suggested to be biologically important in processes such as transcription and translation, gene expression and regulation in human cancer cells, and regulation of telomere length. Investigation of G-quadruplex structures associated with… read more here.
Keywords: spectroscopy analysis; nmr spectroscopy; quadruplex structures; spectroscopy ... See more keywords
Quantification of size effect on protein rotational mobility in cells by 19F NMR spectroscopy
Sign Up to like & getrecommendations! Published in 2017 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-017-0745-4
Abstract: AbstractProtein diffusion in living cells might differ significantly from that measured in vitro. Little is known about the effect of globular protein size on rotational diffusion in cells because each protein has distinct surface properties,… read more here.
Keywords: rotational mobility; protein rotational; effect; size ... See more keywords
19F NMR relaxation studies of fluorosubstituted tryptophans.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of biomolecular NMR"
DOI: 10.1007/s10858-019-00268-y
Abstract: We present 19F longitudinal and transverse relaxation studies for four differently fluorosubstituted L-tryptophans, which carry single F atoms in the indole ring, both in the context of the free amino acid and when located in… read more here.
Keywords: fluorosubstituted tryptophans; relaxation; nmr relaxation; 19f nmr ... See more keywords
Dominant entropic binding of perfluoroalkyl substances (PFASs) to albumin protein revealed by 19F NMR.
Sign Up to like & getrecommendations! Published in 2021 at "Chemosphere"
DOI: 10.1016/j.chemosphere.2020.128083
Abstract: Mechanistic insight into protein binding by poly- and perfluoroalkyl substances (PFASs) is critical to understanding how PFASs distribute and accumulate within the body and to developing predictive models within and across classes of PFASs. Fluorine… read more here.
Keywords: protein; protein binding; perfluoroalkyl substances; 19f nmr ... See more keywords
1H and 19F NMR study of the processes of dissociation of complexes Tm3+ and Ho3+ with ciprofloxacin
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Fluorine Chemistry"
DOI: 10.1016/j.jfluchem.2021.109776
Abstract: Abstract The thermodynamics and kinetics of the dissociation processes of the Tm3+ and complexes with ciprofloxacin were studied by 1H and 19F NMR (at different temperatures). This is one of the few studies on the… read more here.
Keywords: nmr study; study processes; tm3 ho3; dissociation ... See more keywords
19F NMR studies on ionic conduction pathways in tysonite-CeF3
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Physics and Chemistry of Solids"
DOI: 10.1016/j.jpcs.2021.110432
Abstract: Abstract There has been a long-standing controversy over ion conducting pathways in tysonite. To unravel the pathways in CeF3, high-resolution MAS NMR spectra of 19F in CeF3 at −40–240 °C are analyzed on the bases of… read more here.
Keywords: nmr studies; ionic conduction; pathways tysonite; exchange ... See more keywords
Ion mobility and conductivity in the K0.45Bi0.55–In F2.1 solid solutions with fluorite structure according to 19F NMR and conductivity data
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DOI: 10.1016/j.ssi.2018.12.004
Abstract: Abstract Ion mobility and conductivity of K0.45Bi0.55–xInxF2.1 (x = 0, 0.05, 0.1, 0.15) solid solutions with fluorite structure have been investigated using the methods of 19F NMR, X-ray diffraction and impedance spectroscopy. Several types of fluoride ions… read more here.
Keywords: ion mobility; solid solutions; mobility conductivity; conductivity ... See more keywords
Self-diffusion and ionic exchange in mechanosynthesized, nanocrystalline solid solutions of PbF2 and CaF2 19F 2D NMR visualizes the flourine hopping preferences
Sign Up to like & getrecommendations! Published in 2019 at "Solid State Ionics"
DOI: 10.1016/j.ssi.2019.115067
Abstract: Abstract Ionic conductors based on PbF2, being one of the archetypes to study ion dynamics, serve as excellent model substances to study the elementary steps of translational anion dynamics in the solid state. Here, high-energy… read more here.
Keywords: ionic exchange; self diffusion; pbf2 caf2; diffusion ionic ... See more keywords
A Bisboronic Acid Sensor for Ultra-High Selective Glucose Assay by 19F NMR Spectroscopy.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c00262
Abstract: Glucose is a significant analyte both in biology and biomedical science, it is of great importance to selectively detect glucose both in body fluids and complex mixture. In this study, a simple 19F NMR based… read more here.
Keywords: bisboronic acid; sensor ultra; spectroscopy; 19f nmr ... See more keywords
Construction of Lewis Pairs for Optimal Enantioresolution via Recognition-Enabled "Chromatographic" 19F NMR Spectroscopy.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c03783
Abstract: Chirality is a ubiquitous phenomenon in nature, serving as a foundation for a variety of life activities on earth. Separation-free methods that rapidly and accurately distinguish chiral analytes in complex systems are highly demanded in… read more here.
Keywords: chromatographic 19f; spectroscopy; recognition enabled; 19f nmr ... See more keywords