NIMG-36. AUTOMATIC STRATIFICATION OF ENHANCING AND NON-ENHANCING GLIOMAS INTO GENETIC SUBTYPES USING DEEP NEURAL NETWORKS AND DIFFUSION-WEIGHTED IMAGING
Sign Up to like & getrecommendations! Published in 2020 at "Neuro-oncology"
DOI: 10.1093/neuonc/noaa215.649
Abstract: Current WHO guidelines emphasize classification of diffuse gliomas by genetic alterations into three subgroups: 1) IDH-wildtype; 2) IDH-mutant, 1p/19q-codeleted; and 3) IDH-mutant, 1p/19q-non-codeleted. Non-invasive genetic characterization can benefit patients with inoperable lesions or who are… read more here.
Keywords: gliomas genetic; idh mutant; non enhancing; idh wildtype ... See more keywords
Cystathionine as a marker for 1p/19q codeleted gliomas by in vivo magnetic resonance spectroscopy.
Sign Up to like & getrecommendations! Published in 2019 at "Neuro-oncology"
DOI: 10.1093/neuonc/noz031
Abstract: BACKGROUND Codeletion of chromosome arms 1p and 19q (1p/19q codeletion) highly benefits diagnosis and prognosis in gliomas. In this study, we investigated the effect of 1p/19q codeletion on cancer cell metabolism and evaluated possible metabolic… read more here.
Keywords: codeleted gliomas; gliomas; magnetic resonance; cystathionine ... See more keywords
Oligodendrogliomas, IDH-mutant and 1p/19q-codeleted, arising during teenage years often lack TERT promoter mutation that is typical of their adult counterparts
Sign Up to like & getrecommendations! Published in 2018 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-018-0598-x
Abstract: Author(s): Lee, Julieann; Putnam, Angelica R; Chesier, Samuel H; Banerjee, Anuradha; Raffel, Corey; Van Ziffle, Jessica; Onodera, Courtney; Grenert, James P; Bastian, Boris C; Perry, Arie; Solomon, David A read more here.
Keywords: arising teenage; idh mutant; mutant 19q; 19q codeleted ... See more keywords
Extent of resection, molecular signature, and survival in 1p19q-codeleted gliomas.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of neurosurgery"
DOI: 10.3171/2020.2.jns192767
Abstract: OBJECTIVE Genomic analysis in neurooncology has underscored the importance of understanding the patterns of survival in different molecular subtypes within gliomas and their responses to treatment. In particular, diffuse gliomas are now principally characterized by… read more here.
Keywords: extent resection; resection; 19q codeleted; codeleted gliomas ... See more keywords