FISH analysis of brain smears obtained at intraoperative diagnosis – An accurate and fast method to detect 1p/19q-codeletion in gliomas
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2021.07.043
Abstract: The importance of molecular testing of gliomas is highlighted in the 2016 revised 4th edition of the WHO Classification of Tumours of the Central Nervous System, which applies an integrated diagnosis of histological and molecular… read more here.
Keywords: 19q codeletion; fish analysis; method; codeletion ... See more keywords
IDH2 mutations are commonly associated with 1p/19q codeletion in diffuse adult gliomas.
Sign Up to like & getrecommendations! Published in 2018 at "Neuro-oncology"
DOI: 10.1093/neuonc/noy014
Abstract: 716 IDH2 mutations are commonly associated with 1p/19q codeletion in diffuse adult gliomas Diffuse gliomas are classified according to the 2016 World Health Organization (WHO) Classification of Tumors of the Central Nervous System, 1 which… read more here.
Keywords: gliomas; idh2 mutant; 19q codeletion; idh2 ... See more keywords
TERT promoter mutation confers favorable prognosis regardless of 1p/19q status in adult diffuse gliomas with IDH1/2 mutations
Sign Up to like & getrecommendations! Published in 2020 at "Acta Neuropathologica Communications"
DOI: 10.1186/s40478-020-01078-2
Abstract: TERT promoter mutations are commonly associated with 1p/19q codeletion in IDH-mutated gliomas. However, whether these mutations have an impact on patient survival independent of 1p/19q codeletion is unknown. In this study, we investigated the impact… read more here.
Keywords: 19q codeletion; promoter mutation; tert promoter; promoter ... See more keywords
Role of 1p/19q Codeletion in Diffuse Low-grade Glioma Tumour Prognosis
Sign Up to like & getrecommendations! Published in 2023 at "AntiCancer Research"
DOI: 10.21873/anticanres.16432
Abstract: Background/Aim: In the latest 2021 WHO classification of central nervous system tumours (CNS), gliomas that present isocitrate dehydrogenase (IDH) mutations are defined as diffuse low-grade gliomas (DLGGs). IDH mutations are commonly observed in this tumour… read more here.
Keywords: pfs months; 19q codeletion; codeletion; resection ... See more keywords
Radiomics-Based Method for Predicting the Glioma Subtype as Defined by Tumor Grade, IDH Mutation, and 1p/19q Codeletion
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14071778
Abstract: Simple Summary In 2016, the World Health Organization (WHO) recommended the incorporation of molecular parameters, in addition to histology, for an optimal definition of the central nervous system (CNS) tumors. Gliomas, being among the most… read more here.
Keywords: glioma; idh mutation; glioma subtype; 19q codeletion ... See more keywords
Absence of 1p/19q codeletion in oligodendroglioma-like areas of pilocytic astrocytomas.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical neuropathology"
DOI: 10.5414/np301062
Abstract: The presence of oligodendroglioma-like areas in pilocytic astrocytoma may give rise to pathologic diagnostic uncertainty. This study aims to determine if the oligodendroglioma-like areas present in some pilocytic astrocytomas (PA) possess the signature 1p/19q codeletion… read more here.
Keywords: 19q codeletion; oligodendroglioma like; areas pilocytic; pilocytic astrocytomas ... See more keywords