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   Articles with "19q codeletion" as a keyword



FISH analysis of brain smears obtained at intraoperative diagnosis – An accurate and fast method to detect 1p/19q-codeletion in gliomas

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recommendations! Published in 2021 at "Journal of Clinical Neuroscience"

DOI: 10.1016/j.jocn.2021.07.043

Abstract: The importance of molecular testing of gliomas is highlighted in the 2016 revised 4th edition of the WHO Classification of Tumours of the Central Nervous System, which applies an integrated diagnosis of histological and molecular… read more here.

Keywords: 19q codeletion; fish analysis; method; codeletion ... See more keywords

IDH2 mutations are commonly associated with 1p/19q codeletion in diffuse adult gliomas.

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recommendations! Published in 2018 at "Neuro-oncology"

DOI: 10.1093/neuonc/noy014

Abstract: 716 IDH2 mutations are commonly associated with 1p/19q codeletion in diffuse adult gliomas Diffuse gliomas are classified according to the 2016 World Health Organization (WHO) Classification of Tumors of the Central Nervous System, 1 which… read more here.

Keywords: gliomas; idh2 mutant; 19q codeletion; idh2 ... See more keywords

TERT promoter mutation confers favorable prognosis regardless of 1p/19q status in adult diffuse gliomas with IDH1/2 mutations

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recommendations! Published in 2020 at "Acta Neuropathologica Communications"

DOI: 10.1186/s40478-020-01078-2

Abstract: TERT promoter mutations are commonly associated with 1p/19q codeletion in IDH-mutated gliomas. However, whether these mutations have an impact on patient survival independent of 1p/19q codeletion is unknown. In this study, we investigated the impact… read more here.

Keywords: 19q codeletion; promoter mutation; tert promoter; promoter ... See more keywords

Whole-tumor histogram analysis of diffusion weighted imaging, diffusion kurtosis imaging, and intravoxel incoherent motion for adult diffuse glioma genotyping

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recommendations! Published in 2025 at "Cancer Imaging"

DOI: 10.1186/s40644-025-00931-8

Abstract: To evaluate the effectiveness of histogram features from conventional diffusion weighted imaging (DWI), diffusion kurtosis imaging (DKI) and intravoxel incoherent motion (IVIM) parameters in predicting the status of glioma IDH mutation and 1p/19q codeletion based… read more here.

Keywords: 19q codeletion; histogram; kurtosis; idh ... See more keywords

Role of 1p/19q Codeletion in Diffuse Low-grade Glioma Tumour Prognosis

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recommendations! Published in 2023 at "AntiCancer Research"

DOI: 10.21873/anticanres.16432

Abstract: Background/Aim: In the latest 2021 WHO classification of central nervous system tumours (CNS), gliomas that present isocitrate dehydrogenase (IDH) mutations are defined as diffuse low-grade gliomas (DLGGs). IDH mutations are commonly observed in this tumour… read more here.

Keywords: pfs months; 19q codeletion; codeletion; resection ... See more keywords

Incorporation of Edited MRS into Clinical Practice May Improve Care of Patients with IDH-Mutant Glioma

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recommendations! Published in 2024 at "American Journal of Neuroradiology"

DOI: 10.3174/ajnr.a8413

Abstract: Graphical Abstract BACKGROUND AND PURPOSE: Isocitrate dehydrogenase (IDH) mutation and 1p/19q codeletion classify adult-type diffuse gliomas into 3 tumor subtypes with distinct prognoses. We aimed to evaluate the performance of edited MR spectroscopy for glioma… read more here.

Keywords: spectroscopy; 19q codeletion; incorporation edited; idh mutant ... See more keywords

Radiomics-Based Method for Predicting the Glioma Subtype as Defined by Tumor Grade, IDH Mutation, and 1p/19q Codeletion

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recommendations! Published in 2022 at "Cancers"

DOI: 10.3390/cancers14071778

Abstract: Simple Summary In 2016, the World Health Organization (WHO) recommended the incorporation of molecular parameters, in addition to histology, for an optimal definition of the central nervous system (CNS) tumors. Gliomas, being among the most… read more here.

Keywords: glioma; idh mutation; glioma subtype; 19q codeletion ... See more keywords

Absence of 1p/19q codeletion in oligodendroglioma-like areas of pilocytic astrocytomas.

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recommendations! Published in 2018 at "Clinical neuropathology"

DOI: 10.5414/np301062

Abstract: The presence of oligodendroglioma-like areas in pilocytic astrocytoma may give rise to pathologic diagnostic uncertainty. This study aims to determine if the oligodendroglioma-like areas present in some pilocytic astrocytomas (PA) possess the signature 1p/19q codeletion… read more here.

Keywords: 19q codeletion; oligodendroglioma like; areas pilocytic; pilocytic astrocytomas ... See more keywords