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   Articles with "19q deletion" as a keyword



Comparison of 1p and 19q status of glioblastoma by whole exome sequencing, array-comparative genomic hybridization, and fluorescence in situ hybridization

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recommendations! Published in 2018 at "Medical Oncology"

DOI: 10.1007/s12032-018-1119-2

Abstract: According to the 2016 World Health Organization classification of tumors of the central nervous system, detecting 1p/19q co-deletion became essential in clinical neuropathology for gliomas with oligodendroglioma-like morphology. Here, we assessed genomic profiles of glioblastoma… read more here.

Keywords: hybridization; 19q deletion; deletion; situ hybridization ... See more keywords

ATRX immunohistochemistry can help refine ‘not elsewhere classified’ categorisation for grade II/III gliomas

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recommendations! Published in 2019 at "British Journal of Neurosurgery"

DOI: 10.1080/02688697.2019.1600657

Abstract: Abstract Purpose: The 2016 WHO tumour classification highlights the role of IDH1/2 gene mutation and 1p/19q co-deletion in classifying grade II/III gliomas. A recent cIMPACT-NOW update proposes the use of the term ‘Not Elsewhere Classified’… read more here.

Keywords: immunohistochemistry; gliomas; atrx; 19q deletion ... See more keywords

NIMG-01. RADIOMIC DATA ANALYSIS WITH ENSEMBLE MACHINE LEARNING TECHNIQUES PREDICT GRADE, HISTOPATHOLOGIC SUBTYPE, AND 1P/19Q CO-DELETION STATUS IN PATIENTS WITH LOW-GRADE GLIOMAS

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recommendations! Published in 2024 at "Neuro-Oncology"

DOI: 10.1093/neuonc/noae165.0768

Abstract: Low-grade gliomas (LGGs) are a diverse group of primary brain tumors characterized by their variable prognosis and treatment response. Traditionally, the management of LGGs has relied on histopathological analysis, which sometimes offers limited insight into… read more here.

Keywords: 19q deletion; histopathologic subtype; deletion status; grade gliomas ... See more keywords
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Abstract 743: An amplicon sequencing based all-in-one genetic testing panel for molecular classification and guiding individualized treatment of brain cancer

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recommendations! Published in 2020 at "Clinical Trials"

DOI: 10.1158/1538-7445.am2020-743

Abstract: Background: Incorporation of molecular biomarkers and histological features could be applicated for more-precise tumour categorization and individualized treatment. IDH1/2 mutations, 1p/19q co-deletion and TERT-promoter mutations were requisite diagnostic biomarkers for gliomas classification. BRAF V600E mutation… read more here.

Keywords: 19q deletion; deletion; biomarkers panel; cancer ... See more keywords

Thin-Slice Magnetic Resonance Imaging-Based Radiomics Signature Predicts Chromosomal 1p/19q Co-deletion Status in Grade II and III Gliomas

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recommendations! Published in 2020 at "Frontiers in Neurology"

DOI: 10.3389/fneur.2020.551771

Abstract: Objective: Chromosomal 1p/19q co-deletion is recognized as a diagnostic, prognostic, and predictive biomarker in lower grade glioma (LGG). This study aims to construct a radiomics signature to non-invasively predict the 1p/19q co-deletion status in LGG.… read more here.

Keywords: 19q deletion; radiomics signature; deletion status; signature ... See more keywords