Comparison of 1p and 19q status of glioblastoma by whole exome sequencing, array-comparative genomic hybridization, and fluorescence in situ hybridization
Sign Up to like & getrecommendations! Published in 2018 at "Medical Oncology"
DOI: 10.1007/s12032-018-1119-2
Abstract: According to the 2016 World Health Organization classification of tumors of the central nervous system, detecting 1p/19q co-deletion became essential in clinical neuropathology for gliomas with oligodendroglioma-like morphology. Here, we assessed genomic profiles of glioblastoma… read more here.
Keywords: hybridization; 19q deletion; deletion; situ hybridization ... See more keywords
Arterial Spin Labeling for Glioma Grade Discrimination: Correlations with IDH1 Genotype and 1p/19q Status
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DOI: 10.1016/j.tranon.2019.02.013
Abstract: Since accurate grading of gliomas has important clinical value, the aim of this study is to evaluate the diagnostic efficacy of perfusion values derived from arterial spin labeling (ASL) to grade gliomas. In addition, the… read more here.
Keywords: gliomas; perfusion; arterial spin; spin labeling ... See more keywords
HIP1R and Vimentin immunohistochemistry predict 1p/19q status in IDH-mutant glioma.
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DOI: 10.1093/neuonc/noac111
Abstract: BACKGROUND IDH-mutant gliomas are separate based on the codeletion of the chromosomal arms 1p and 19q into oligodendrogliomas IDH-mutant 1p/19q-codeleted and astrocytomas IDH-mutant. While nuclear loss of ATRX expression excludes 1p/19q codeletion, its limited sensitivity… read more here.
Keywords: idh mutant; immunohistochemistry; vimentin; idh ... See more keywords