Identification of novel cell-impermeant fluorescent substrates for testing the function and drug interaction of Organic Anion-Transporting Polypeptides, OATP1B1/1B3 and 2B1
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DOI: 10.1038/s41598-018-20815-1
Abstract: Organic Anion-Transporting Polypeptides are multispecific membrane proteins that regulate the passage of crucial endobiotics and drugs across pharmacological barriers. OATP1B1 and OATP1B3 have been described to play a major role in the hepatic uptake of… read more here.
Keywords: 1b3 2b1; oatp1b1 1b3; transporting polypeptides; anion transporting ... See more keywords