LncRNA TUG1 reduces inflammation and enhances insulin sensitivity in white adipose tissue by regulating miR-204/SIRT1 axis in obesity mice.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular and cellular biochemistry"
DOI: 10.1007/s11010-020-03869-6
Abstract: Prevalence of obesity becomes an important health issue worldwide, but the management of obesity remains unsatisfied. This study aimed to explore the mechanism of long non-coding RNA TUG/miR-204/SIRT1 axis, which was involved in the pathogenesis… read more here.
Keywords: tug1; obesity; inflammation; 204 sirt1 ... See more keywords
Astragalus polysaccharide attenuates metabolic memory-triggered ER stress and apoptosis via regulation of miR-204/SIRT1 axis in retinal pigment epithelial cells
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DOI: 10.1042/bsr20192121
Abstract: Abstract Background: ‘Metabolic memory’ of early hyperglycaemic environment has been frequently suggested in the progression of diabetic retinopathy (DR). Retinal pigment epithelial (RPE) cells are crucial targets for DR initiation following hyperglycaemia. Astragalus polysaccharides (APS)… read more here.
Keywords: 204 sirt1; mir 204; metabolic memory; apoptosis ... See more keywords
Candidate oncogene circularNOP10 mediates gastric cancer progression by regulating miR-204/SIRT1 pathway.
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DOI: 10.21037/jgo-21-422
Abstract: Background The role of circular RNA (circRNA) in gastric cancer (GC) is attracting increasing attention. CircNOP10 (hsa_circ-0034351) has been reported to be upregulated in human GC tissue. However, the biological role and mechanism of circNOP10… read more here.
Keywords: circnop10; gastric cancer; 204 sirt1; sirt1 pathway ... See more keywords