Targeting epigenetic pathway with gold nanoparticles for acute myeloid leukemia therapy.
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DOI: 10.1016/j.biomaterials.2018.03.013
Abstract: Leukemia remains a fatal disease for most patients and novel therapeutic strategies are urgently needed. Aberrant DNA methylation is an epigenetic modification that is important in the initiation and progression of leukemia. Here, we demonstrated… read more here.
Keywords: myeloid leukemia; mir 221; ncl mir; 221 dnmt1 ... See more keywords