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Ketoconazole- and Metyrapone-Induced Reductions on Urinary Steroid Metabolites Alter the Urinary Free Cortisol Immunoassay Reliability in Cushing Syndrome

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Published in 2022 at "Frontiers in Endocrinology"

DOI: 10.3389/fendo.2022.833644

Abstract: Introduction Twenty-four-hour urinary free cortisol (24h-UFC) is the most used test for follow-up decision-making in patients with Cushing syndrome (CS) under medical treatment. However, 24h-UFC determinations by immunoassays (IA) are commonly overestimated because of steroid… read more here.

Keywords: steroid metabolites; 24h ufc; urinary steroid; mtp ... See more keywords