Articles with "254890 fr900359" as a keyword



Structure-activity relationship and conformational studies of the natural product cyclic depsipeptides YM-254890 and FR900359.

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Published in 2018 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2018.07.023

Abstract: G proteins are key mediators in the signaling of G protein-coupled receptors and involved in a plethora of important physiological processes. The natural product cyclic depsipeptides YM-254890 and FR900359 are the only known selective inhibitors… read more here.

Keywords: 254890 fr900359; depsipeptides 254890; cyclic depsipeptides; natural product ... See more keywords