Hallucinogen-Like Action of the Novel Designer Drug 25I-NBOMe and Its Effect on Cortical Neurotransmitters in Rats
Sign Up to like & getrecommendations! Published in 2019 at "Neurotoxicity Research"
DOI: 10.1007/s12640-019-00033-x
Abstract: NBOMes are N-benzylmethoxy derivatives of the 2C family hallucinogens. 4-Iodo-2,5-dimethoxy-N-(2-methoxybenzyl)phenethylamine (25I-NBOMe) is one of the commonly used illicit drugs. It exhibits high binding affinity for 5-HT2A/C and 5-HT1A serotonin receptors. Activation of 5-HT2A receptor induces… read more here.
Keywords: 25i nbome; tissue; drug; effect ... See more keywords
The differentiation of 2,5-dimethoxy-N-(N-methoxybenzyl)phenethylamine (NBOMe) isomers using GC retention indices and multivariate analysis of ion abundances in electron ionization mass spectra
Sign Up to like & getrecommendations! Published in 2019 at "Forensic Chemistry"
DOI: 10.1016/j.forc.2019.100160
Abstract: Abstract Synthetic phenethylamine derivatives known as 2,5-dimethoxy-N-(N-methoxybenzyl)phenethylamines (NBOMes) are a common class of novel psychoactive substances (NPS) that are causing many accidental deaths across the United States. Many derivatives are now banned at the federal… read more here.
Keywords: retention; ion; 25c nbome; retention indices ... See more keywords
Recreational drugs 25I-NBOH and 25I-NBOMe bind to both Sudlow's sites I and II of human serum albumin (HSA): biophysical and molecular modeling studies
Sign Up to like & getrecommendations! Published in 2021 at "New Journal of Chemistry"
DOI: 10.1039/d1nj00806d
Abstract: 25I-NBOH and 25I-NBOMe simultaneously bind to sites I and II of HSA, which may affect their distribution and effects. read more here.
Keywords: 25i nbome; nboh 25i; nbome bind; 25i nboh ... See more keywords
25I-NBOME (2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine)-A HARMFUL HALLUCINOGEN REVIEW.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of analytical toxicology"
DOI: 10.1093/jat/bkaa022
Abstract: NBOMes are N-benzylmethoxy derivatives of the 2C family compounds with N-2-methoxy-benzyl moiety substituted by the methoxy group at the 2- and 5- position and the halogen group at the 4- position of the phenyl ring.… read more here.
Keywords: 25i nbome; dimethoxyphenyl methoxyphenyl; methoxyphenyl methyl; review ... See more keywords
Locomotor and discriminative stimulus effects of four novel hallucinogens in rodents
Sign Up to like & getrecommendations! Published in 2017 at "Behavioural Pharmacology"
DOI: 10.1097/fbp.0000000000000309
Abstract: There has been increasing use of novel synthetic hallucinogenic compounds, 2-(4-bromo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine hydrochloride (25B-NBOMe), 2-(4-chloro-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine hydrochloride (25C-NBOMe), 2-(4-iodo-2,5-dimethoxyphenyl)-N-(2-methoxybenzyl)ethanamine hydrochloride (25I-NBOMe), and N,N-diallyl-5-methoxy tryptamine (5-MeO-DALT), which have been associated with severe toxicities. These four compounds were tested… read more here.
Keywords: 25i nbome; fully substituted; dom; nbome fully ... See more keywords
Retrospective Demonstration of 25I-NBOMe Acute Poisoning Using Hair Analysis.
Sign Up to like & getrecommendations! Published in 2017 at "Current pharmaceutical biotechnology"
DOI: 10.2174/1389201019666171129175148
Abstract: BACKGROUND The abuse of new psychoactive substances or NPS has been dramatically increasing all around the world since the last half of the year 2000 and has become a serious public health problem. NPS are… read more here.
Keywords: 25i nbome; hair; demonstration 25i; hair analysis ... See more keywords