Inhibition of human N myristoyltransferase 1 as a strategy to suppress cancer progression driven by myristoylation
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DOI: 10.1038/s41598-025-13529-8
Abstract: N-myristoyltransferase 1 (NMT-1) catalyzes the co-translational addition of myristic acid to the N-terminal glycine of substrate proteins, regulating membrane localization and protein-protein interactions essential for oncogenic signaling. Its overexpression in diverse malignancies has rendered NMT-1… read more here.
Keywords: 289 547; human myristoyltransferase; myristoyltransferase; myristoyltransferase strategy ... See more keywords