The protective effects of thymol and carvacrol against di (2‐ethylhexyl) phthalate‐induced cytotoxicity in HEK‐293 cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23092
Abstract: The protective effects of thymol and carvacrol, two phenolic monoterpenes with a wide spectrum of pharmacological effects, against the oxidative stress produced by the di (2‐ethylhexyl) phthalate (DEHP) in human embryonic kidney cells 293 cells… read more here.
Keywords: protective effects; 293 cells; thymol carvacrol; hek 293 ... See more keywords
Genetic and functional analysis of the RYR1 mutation p.Thr84Met revealed a susceptibility to malignant hyperthermia
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Anesthesia"
DOI: 10.1007/s00540-018-2451-6
Abstract: PurposeThe aim of this study was to analyze the genetic and functional role of a novel RYR1 variant c.251 C > T (p.Thr84Met) identified in a patient with muscle weakness demonstrating MH susceptibility.MethodsDNA testing of family members… read more here.
Keywords: susceptibility; 293 cells; genetic functional; ryr1 ... See more keywords
Olive compounds attenuate oxidative damage induced in HEK-293 cells via MAPK signaling pathway
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Functional Foods"
DOI: 10.1016/j.jff.2017.10.008
Abstract: Abstract The protective effects of ethanolic olive fruit extract (OFE) and purified oleuropein (Ole) have been evaluated against H2O2-induced oxidative damage and apoptosis in human embryonic kidney (HEK-293) cells. Olive compounds demonstrated a protective effect… read more here.
Keywords: 293 cells; oxidative damage; olive compounds; signaling pathway ... See more keywords
Purification and characterization of a bioactive alpha-fetoprotein produced by HEK-293 cells.
Sign Up to like & getrecommendations! Published in 2017 at "Protein expression and purification"
DOI: 10.1016/j.pep.2017.05.008
Abstract: Alpha-fetoprotein (AFP) is a biomarker that is used to diagnose hepatocellular carcinoma (HCC) and can promote malignancy in HCC. AFP is an important target in the treatment of liver cancer. To obtain enough AFP to… read more here.
Keywords: afp; 293 cells; hek 293; alpha fetoprotein ... See more keywords
Disulfide isomerase ERp57 improves the stability and immunogenicity of H3N2 influenza virus hemagglutinin
Sign Up to like & getrecommendations! Published in 2020 at "Virology Journal"
DOI: 10.1186/s12985-020-01325-x
Abstract: Background Hemagglutinin (HA), as the surface immunogenic protein, is the most important component of influenza viruses. Previous studies showed that the stability of HA was significant for HA’s immunogenicity, and many efforts have been made… read more here.
Keywords: immunogenicity; 293 cells; disulfide; immunogenicity h3n2 ... See more keywords
Effects of equol on multiple K+ channels stably expressed in HEK 293 cells
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0183708
Abstract: The present study investigated the effects of equol on cardiovascular K+ channel currents. The cardiovascular K+ channel currents were determined in HEK 293 cells stably expressing cloned differential cardiovascular K+ channels with conventional whole-cell patch… read more here.
Keywords: multiple channels; 293 cells; equol multiple; effects equol ... See more keywords
Thapsigargin blocks electromagnetic field‐elicited intracellular Ca2+ increase in HEK 293 cells
Sign Up to like & getrecommendations! Published in 2022 at "Physiological Reports"
DOI: 10.14814/phy2.15189
Abstract: Biological effects of electromagnetic fields (EMFs) have previously been identified for cellular proliferation and changes in expression and conduction of diverse types of ion channels. The major effect elicited by EMFs seems to be directed… read more here.
Keywords: thapsigargin blocks; increase; 293 cells; intracellular ca2 ... See more keywords
Evaluation of the cytotoxic and genotoxic effects by melamine and cyanuric acid co-exposure in human embryonic kidney 293 cells
Sign Up to like & getrecommendations! Published in 2020 at "Brazilian Journal of Medical and Biological Research"
DOI: 10.1590/1414-431x20209331
Abstract: The melamine and cyanuric acid (CA) complex has been suggested to cause the toxic effects observed in melamine-contaminated food or milk. However, the cytotoxic and genotoxic effects of co-exposure to melamine and CA are not… read more here.
Keywords: melamine; effects melamine; 293 cells; cytotoxic genotoxic ... See more keywords
Effect of trans-sodium crocetinate on contrast-induced cytotoxicity in HEK-293 cells
Sign Up to like & getrecommendations! Published in 2023 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2022.64671.14234
Abstract: Objective(s): Contrast media (CM) are used for diagnostic or therapeutic intervention purposes in medicine. The main adverse reaction after the administration of CM is contrast-induced nephropathy (CIN). This complication is the third cause of renal… read more here.
Keywords: induced cytotoxicity; 293 cells; hek 293; contrast induced ... See more keywords
Trans-sodium crocetinate suppresses apoptotic and oxidative response following myoglobin-induced cytotoxicity in HEK-293 cells
Sign Up to like & getrecommendations! Published in 2024 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2024.75306.16322
Abstract: Objective(s): Rhabdomyolysis (RM) is a serious fatal syndrome. The RM leads to acute kidney injury (AKI) as a fatal complication. The belief is that RM-induced AKI is triggered by myoglobin (MB). MB activates oxidative and… read more here.
Keywords: 293 cells; cytotoxicity hek; hek 293; induced cytotoxicity ... See more keywords
Gαq-Stimulated Gene Expression Is Insensitive to Bromo Extra Terminal Domain Inhibitors in HEK 293 Cells
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms26188904
Abstract: Bromodomain and extraterminal domain (BET) family proteins are ubiquitous transcriptional co-activators that function broadly in gene expression programs associated with cellular differentiation, proliferation, and stress responses. Pharmacological inhibition of BET proteins with small molecules that… read more here.
Keywords: 293 cells; hek 293; gene expression; expression ... See more keywords