Evaluation of Omeprazole Limited Sampling Strategies to Estimate Constitutive Cytochrome P450 2C19 Activity in Healthy Adults
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DOI: 10.1097/ftd.0000000000000554
Abstract: Background: Limited sampling strategy (LSS) is a validated method to estimate pharmacokinetic (PK) parameters from a reduced number of samples. Omeprazole is used to phenotype in vivo cytochrome P450 (CYP) 2C19 activity. This study examined… read more here.
Keywords: 2c19 activity; limited sampling; cytochrome p450; activity ... See more keywords