The Structure of the Dimeric State of IscU Harboring Two Adjacent [2Fe-2S] Clusters Provides Mechanistic Insights into Cluster Conversion to [4Fe-4S].
Sign Up to like & getrecommendations! Published in 2021 at "Biochemistry"
DOI: 10.1021/acs.biochem.1c00112
Abstract: IscU serves as a scaffold for the de novo assembly of a [2Fe-2S] cluster prior to its delivery to recipient protein. It has also been proposed that on one dimer of bacterial IscU, two [2Fe-2S]… read more here.
Keywords: dimeric state; 2fe clusters; state iscu; conversion ... See more keywords
Sulfur-Ligated [2Fe-2C] Clusters as Synthetic Model Systems for Nitrogenase
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DOI: 10.1021/acs.inorgchem.2c03693
Abstract: Metal clusters featuring carbon and sulfur donors have coordination environments comparable to the active site of nitrogenase enzymes. Here, we report a series of di-iron clusters supported by the dianionic yldiide ligands, in which the… read more here.
Keywords: model systems; synthetic model; ligated 2fe; 2fe clusters ... See more keywords
A VDAC1-mediated NEET protein chain transfers [2Fe-2S] clusters between the mitochondria and the cytosol and impacts mitochondrial dynamics
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2121491119
Abstract: Significance Here we address the important question of cross-talk between the mitochondria and cytosol. We show that the inner mitochondrial protein, MiNT, interacts with a protein on the outer mitochondrial membrane (mNT). This interaction occurs… read more here.
Keywords: mitochondria cytosol; transfers 2fe; neet protein; 2fe clusters ... See more keywords