Complement activity and complement regulatory gene mutations are associated with thrombosis in APS and CAPS.
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DOI: 10.1182/blood.2019003863
Abstract: The antiphospholipid syndrome (APS) is characterized by thrombosis and/or pregnancy morbidity in the presence of antiphospholipid antibodies including anti-beta-2-glycoprotein-I (anti-β2GPI) that are considered central to APS pathogenesis. Based on animal studies showing a role of… read more here.
Keywords: 2gpi antibodies; anti 2gpi; complement regulatory; complement ... See more keywords