Biophysical Characterization of LTX-315 Anticancer Peptide Interactions with Model Membrane Platforms: Effect of Membrane Surface Charge
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DOI: 10.3390/ijms231810558
Abstract: LTX-315 is a clinical-stage, anticancer peptide therapeutic that disrupts cancer cell membranes. Existing mechanistic knowledge about LTX-315 has been obtained from cell-based biological assays, and there is an outstanding need to directly characterize the corresponding… read more here.
Keywords: ltx 315; spectroscopy; anticancer peptide; membrane ... See more keywords