A microRNA Cluster Controls Fat Cell Differentiation and Adipose Tissue Expansion By Regulating SNCG
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DOI: 10.1002/advs.202104759
Abstract: The H19X‐encoded miR‐424(322)/503 cluster regulates multiple cellular functions. Here, it is reported for the first time that it is also a critical linchpin of fat mass expansion. Deletion of this miRNA cluster in mice results… read more here.
Keywords: differentiation; 424 322; cluster; 322 503 ... See more keywords
TNF Signaling Acts Downstream of MiR-322/-503 in Regulating DM1 Myogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2022.843202
Abstract: Myotonic dystrophy type 1 (DM1) is caused by the expanded CUG repeats and usually displays defective myogenesis. Although we previously reported that ectopic miR-322/-503 expression improved myogenesis in DM1 by targeting the toxic RNA, the… read more here.
Keywords: tnf signaling; myogenesis; dm1; 322 503 ... See more keywords