Structural Basis for the Inhibition of Mycobacterial MmpL3 by NITD-349 and SPIRO.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of molecular biology"
DOI: 10.1016/j.jmb.2020.05.019
Abstract: Novel antitubercular agents are urgently needed to combat the emergence of global drug resistance to human tuberculosis (TB). Mycobacterial membrane protein Large 3 (MmpL3) is a promising drug target because its activity is essential and… read more here.
Keywords: structural basis; basis inhibition; 349 spiro; drug ... See more keywords