Articles with "34a mir" as a keyword



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Senescence-associated miR-34a and miR-126 in middle-aged Indians with type 2 diabetes

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Published in 2019 at "Clinical and Experimental Medicine"

DOI: 10.1007/s10238-019-00593-4

Abstract: Rapid urbanization and unhealthy dietary patterns critically increase the risk of type 2 diabetes (T2D) in middle-aged Indians. However, despite recent evidence of senescence-associated microRNAs (SA-miRNAs) in regulating complex pathways of ageing, their expressions in middle-aged… read more here.

Keywords: mir 126; senescence associated; mir 34a; middle aged ... See more keywords
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Shikonin-mediated up-regulation of miR-34a and miR-202 inhibits retinoblastoma proliferation.

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Published in 2018 at "Toxicology research"

DOI: 10.1039/c8tx00079d

Abstract: Retinoblastoma (RB) is an ocular tumor that occurs mainly in children. The pathogenesis of RB is not well understood, and its treatment strategies are very limited. Shikonin is widely reported as an anti-tumor agent. However,… read more here.

Keywords: mir 34a; mir; proliferation; shikonin ... See more keywords
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PU.1-deficient mice are resistant to thioacetamide-induced hepatic fibrosis: PU.1 finely regulates Sirt1 expression via transcriptional promotion of miR-34a and miR-29c in hepatic stellate cells

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Published in 2017 at "Bioscience Reports"

DOI: 10.1042/bsr20170926

Abstract: PU box binding protein (PU.1) is a critical transcription factor involved in many pathological processes. However, its exact role in activation of hepatic stellate cells (HSCs) and liver fibrosis was rarely reported. Here, we found… read more here.

Keywords: hscs; fibrosis; mir 34a; mice ... See more keywords
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Abstract 4448: Elevated levels of circulating miR-34a-5p and miR-181c-3p during cancer initiation by aflatoxin B1

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Published in 2017 at "Cancer Research"

DOI: 10.1158/1538-7445.am2017-4448

Abstract: MicroRNAs are small non-coding RNAs that affect gene expression. They are essential in normal physiological processes and have been implicated in carcinogenesis. Hepatocellular carcinoma (HCC) is the second leading cause of cancer death globally, with… read more here.

Keywords: mir 34a; mir; mir 181c; cancer initiation ... See more keywords
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Abstract 4749: Effects of miR-34a-5p and miR-181b-5p silencing and induction on their potential targets in uterine leiomyosarcoma cells

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-4749

Abstract: Background: Leiomyosarcoma (LMS) is a malignant tumor of the uterine body that represents 40-60% of all gynecological sarcomas. Up to now, there is no specific treatment or diagnostic biomarkers for this tumor. The identification and… read more here.

Keywords: mir 181b; expression; treatment; mir 34a ... See more keywords
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Serum miR-34a-5p and miR-199a-3p as new biomarkers of neonatal sepsis

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Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0262339

Abstract: Background Neonatal sepsis is a serious condition. Recent clinical studies have indicated that microRNAs (miRNAs) are key players in the pathogenesis of sepsis, which could be used as biomarkers for this condition. Patients and methods… read more here.

Keywords: sepsis; serum mir; mir 199a; neonatal sepsis ... See more keywords
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The correlation between miR -34a-3p, miR -31, PLEK2 and the occurrence, development and prognosis of colorectal cancer.

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Published in 2022 at "Cellular and molecular biology"

DOI: 10.14715/cmb/2022.68.1.23

Abstract: The current study aimed to explore the correlation between Mir-34A-3p, Mir-31, PLEK2 and the occurrence, development and prognosis of colorectal cancer. For this paper, 120 patients with colorectal cancer were selected as the study group,… read more here.

Keywords: plek2; colorectal cancer; mir; mir 34a ... See more keywords
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Inter-correlation of lncRNA THRIL with microRNA-34a and microRNA-125b and their relationship with childhood asthma risk, severity, and inflammation.

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Published in 2023 at "Allergologia et immunopathologia"

DOI: 10.15586/aei.v51i1.736

Abstract: BACKGROUND Long noncoding RNA (lncRNA) THRIL targets microRNA (miR)-34a and miR-125b to modify immunity, inflammation, and respiratory injury. The current study aimed to determine the inter-correlation of lncRNA THRIL with miR-34a and miR-125b and their… read more here.

Keywords: mir 125b; lncrna thril; mir; mir 34a ... See more keywords