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Coformulation of Broadly Neutralizing Antibodies 3BNC117 and PGT121: Analytical Challenges During Preformulation Characterization and Storage Stability Studies

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Published in 2018 at "Journal of Pharmaceutical Sciences"

DOI: 10.1016/j.xphs.2018.08.012

Abstract: In this study, we investigated analytical challenges associated with the formulation of 2 anti-HIV broadly neutralizing antibodies (bnAbs), 3BNC117 and PGT121, both separately at 100 mg/mL and together at 50 mg/mL each. The bnAb formulations… read more here.

Keywords: stability studies; analytical challenges; 3bnc117 pgt121; neutralizing antibodies ... See more keywords