Articles with "3t3 cells" as a keyword



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Naringin prevents ultraviolet‐B radiation‐induced oxidative damage and inflammation through activation of peroxisome proliferator‐activated receptor γ in mouse embryonic fibroblast (NIH‐3T3) cells

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Published in 2019 at "Journal of Biochemical and Molecular Toxicology"

DOI: 10.1002/jbt.22263

Abstract: The present study, we investigate the preventive role of naringin, a dietary flavonoid, against ultraviolet‐B (UVB) radiation (280‐320 nm) induced oxidative damage and inflammatory responses in mouse embryonic fibroblast cell lines (NIH‐3T3). In this study, 20 mJ/cm… read more here.

Keywords: nih 3t3; oxidative damage; naringin prevents; 3t3 cells ... See more keywords
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β-Cypermethrin Alleviated the Inhibitory Effect of Medium from RAW 264.7 Cells on 3T3-L1 Cell Maturation into Adipocytes.

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Published in 2020 at "Lipids"

DOI: 10.1002/lipd.12234

Abstract: Studies have elucidated that pyrethroids induce adipogenesis. It is also known that macrophages can affect the homeostasis of adipose tissue. However, whether and how the β-cypermethrin (β-CYP)-mediated inhibition of the macrophages affects adipogenesis remain unknown.… read more here.

Keywords: raw 264; inhibitory effects; 264 cells; 3t3 cells ... See more keywords
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Visualization of Intracellular Hydrogen Peroxide with the Genetically Encoded Fluorescent Probe HyPer in NIH-3T3 Cells.

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Published in 2019 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-9424-3_15

Abstract: Reactive oxygen species (ROS) are involved in regulating normal physiological cell functions as second messengers as well as nonspecific damage of biomolecules in a pathological process known as oxidative stress. The HyPer family of genetically… read more here.

Keywords: nih 3t3; probe; hydrogen peroxide; genetically encoded ... See more keywords
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Expression of genes associated with inflammation and iron metabolism in 3T3-L1 cells induced with macrophages-conditioned medium, glucose and iron

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Published in 2018 at "BioMetals"

DOI: 10.1007/s10534-018-0108-4

Abstract: Obesity is characterized by a chronic inflammatory process, with an increased volume of total adipose tissue, especially visceral, which secretes pro-inflammatory cytokines such as TNF-α and IL-6. Hepcidin (Hpc), a main iron metabolism regulator, is… read more here.

Keywords: conditioned medium; iron metabolism; glucose iron; iron ... See more keywords
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Anti-obesity effects of kaempferol by inhibiting adipogenesis and increasing lipolysis in 3T3-L1 cells

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Published in 2018 at "Journal of Physiology and Biochemistry"

DOI: 10.1007/s13105-018-0659-4

Abstract: Kaempferol is a natural flavonoid widely found in fruits, vegetables, and tea. Kaempferol possesses beneficial biological properties such as anti-inflammatory and antioxidant activities. Positive energy balance during obesity correlates with a pro-inflammatory chronic state. In… read more here.

Keywords: anti obesity; kaempferol; adipogenesis; expression ... See more keywords
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Suppression of CD36 attenuates adipogenesis with a reduction of P2X7 expression in 3T3-L1 cells.

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Published in 2017 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2017.07.077

Abstract: Adipogenesis is a process of differentiation from preadipocyte into adipocyte, and is regulated by several transcription factors, including the peroxisome proliferator-activated receptor gamma (PPARγ) and the CCAAT-enhancer-binding protein alpha (C/EBPα). CD36 is a membrane protein… read more here.

Keywords: suppression cd36; attenuates adipogenesis; cd36 attenuates; cd36 ... See more keywords
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Knocking down Stard3 decreases adipogenesis with decreased mitochondrial ROS in 3T3-L1 cells.

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Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.06.030

Abstract: Start domain-containing protein 3 (Stard3) plays roles in intracellular cholesterol distribution, however, the role of Stard3 in the adipogenesis of 3T3-L1 preadipocytes remains unclear. We demonstrated that Stard3 expression was significantly increased during the adipogenesis… read more here.

Keywords: mitochondrial ros; stard3; adipogenesis; 3t3 cells ... See more keywords
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A Dual Fluorescent 3-D Multicellular Coculture of Breast Cancer MCF-7 and Fibroblast NIH-3T3 Cells for High Throughput Cancer Drug Screening

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Published in 2019 at "Biochemical Engineering Journal"

DOI: 10.1016/j.bej.2019.05.007

Abstract: Abstract Tumor microenvironment plays a vital role in tumor progression, metastasis and aggressiveness. The interaction between tumor and surrounding stromal cells, especially fibroblasts, is closely related to antitumor drug sensitivity. We developed a novel 3-dimensional… read more here.

Keywords: mcf; drug; coculture; cancer ... See more keywords
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Epigallocatechin‐3‐gallate inhibits adipogenesis through down‐regulation of PPAR&ggr; and FAS expression mediated by PI3K‐AKT signaling in 3T3‐L1 cells

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Published in 2017 at "European Journal of Pharmacology"

DOI: 10.1016/j.ejphar.2016.12.006

Abstract: ABSTRACT Epigallocatechin‐3‐gallate (EGCG), a major component in green tea, functions as extensive bioactivities including anti‐inflammation, anti‐oxidation, and anti‐cancer. However, little is known about its anti‐adipogenesis and underlying mechanisms. The purport of this study sought to… read more here.

Keywords: akt; adipogenesis; ggr fas; ppar ggr ... See more keywords
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Colocynth (Citrullus colocynthis) seed extracts attenuate adipogenesis by down-regulating PPARγ/ SREBP-1c and C/EBPα in 3T3-L1 cells

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Published in 2020 at "Food bioscience"

DOI: 10.1016/j.fbio.2019.100491

Abstract: Abstract Adipogenesis is the overall process of adipocyte differentiation. With a positive energy balance, intracellular accumulation of triglyceride increases through the generation of functional adipocytes. This occurs with adipogenesis of undifferentiated preadipocytes. Citrullus colocynthis (CC),… read more here.

Keywords: seed; citrullus colocynthis; adipogenesis; colocynth citrullus ... See more keywords
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Cynandione A induces adipogenesis and beige adipocyte-related phenotype in 3T3-L1 cells

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Published in 2020 at "Phytochemistry Letters"

DOI: 10.1016/j.phytol.2020.07.011

Abstract: Abstract Cynandione A (CA) is a major ingredient of Cynanchum wilfordii. Here, we report a new function of CA in adipogenesis in 3T3-L1 cells, a preadipocyte cell line. During adipogenic differentiation in 3T3-L1 cells, CA… read more here.

Keywords: adipocyte; adipocyte related; beige adipocyte; induces adipogenesis ... See more keywords