Articles with "3t3 preadipocytes" as a keyword



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Orphan receptor GPR50 attenuates inflammation and insulin signaling in 3T3‐L1 preadipocytes

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Published in 2022 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.13516

Abstract: Type 2 diabetes (T2DM) is characterized by insulin secretion deficiencies and systemic insulin resistance (IR) in adipose tissue, skeletal muscle, and the liver. Although the mechanism of T2DM is not yet fully known, inflammation and… read more here.

Keywords: 3t3 preadipocytes; insulin signaling; receptor; gpr50 ... See more keywords
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Lanthanum nitrate inhibits adipogenesis in 3T3‐L1 preadipocytes with a disorder of mitotic clonal expansion process

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Published in 2022 at "Journal of Applied Toxicology"

DOI: 10.1002/jat.4391

Abstract: Lanthanum (La) as a rare earth element is widely used in agriculture, industry, and medicine. It has been suggested in several studies that La might influence glycolipid metabolism in vivo. In this study, we used… read more here.

Keywords: mitotic clonal; clonal expansion; 3t3 preadipocytes; lanthanum ... See more keywords
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PINK1-Parkin alleviates metabolic stress induced by obesity in adipose tissue and in 3T3-L1 preadipocytes.

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Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.02.199

Abstract: Mitochondria play an important role in cellular metabolism and are closely related with metabolic stress. Recently, several studies have shown that mitophagy mediated by PTEN-induced putative kinase 1 (PINK1) and Parkin may play a critical… read more here.

Keywords: pink1 parkin; 3t3 preadipocytes; adipose tissue; metabolic stress ... See more keywords
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Apple phlorizin oxidation product 2 inhibits proliferation and differentiation of 3T3-L1 preadipocytes

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Published in 2019 at "Journal of Functional Foods"

DOI: 10.1016/j.jff.2019.103525

Abstract: Abstract Phlorizin is a natural polyphenol with many bioactivities, however, its low water solubility limits its application. Phlorizin oxidation product 2 (POP2) has higher water solubility than phlorizin. However, reaction velocity and conversion rate of… read more here.

Keywords: pop2; 3t3 preadipocytes; oxidation product; phlorizin oxidation ... See more keywords
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Dexamethasone induced miR-155 up-regulation in differentiating 3T3-L1 preadipocytes does not affect adipogenesis

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Published in 2018 at "Scientific Reports"

DOI: 10.1038/s41598-018-19704-4

Abstract: Dexamethasone is a synthetic glucocorticoid that is widely used as an adipogenic inducer in both murine and human in vitro models. Glucocorticoids have been shown to regulate early transcriptional events in adipogenesis. MicroRNAs (miRNAs) have… read more here.

Keywords: 3t3 preadipocytes; differentiating 3t3; mir 155; adipogenesis ... See more keywords
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Anti-obesity effects of corn peptide on 3T3-L1 preadipocytes and C57BL/6J obese mice

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Published in 2022 at "Archives of Animal Nutrition"

DOI: 10.1080/1745039x.2022.2162800

Abstract: ABSTRACT Corn peptide (CP) is a small, natural, biologically active peptide obtained by protease-catalysed hydrolysis of corn. CP exerts antihypertensive, hypoglycaemic, antihyperlipidemic, antioxidant, and antitumor effects, as well as prevents cardiovascular and cerebrovascular diseases. Although… read more here.

Keywords: c57bl obese; corn; corn peptide; obese mice ... See more keywords

Chrysanthemum indicum suppresses adipogenesis by inhibiting mitotic clonal expansion in 3T3-L1 preadipocytes.

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Published in 2021 at "Journal of food biochemistry"

DOI: 10.1111/jfbc.13896

Abstract: Herbs have been of interest to treat diseases, including obesity, owing to their various bioactive constituents that exhibit therapeutic and prophylactic properties. The present study examined the anti-adipogenic effects and mechanisms of Chrysanthemum indicum aqueous… read more here.

Keywords: 3t3 preadipocytes; clonal expansion; cae; mitotic clonal ... See more keywords

Epigallocatechin Gallate Effectively Affects Senescence and Anti-SASP via SIRT3 in 3T3-L1 Preadipocytes in Comparison with Other Bioactive Substances

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Published in 2020 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2020/4793125

Abstract: Aim We investigated different bioactive compounds including epigallocatechin gallate (EGCG), anthocyanidin, resveratrol, phloretin, spermidine, butyrate, and β-hydroxybutyrate with regard to their effect on SIRT3 via NRF2 and modulation of the proinflammatory senescence-associated secretory phenotype (SASP)… read more here.

Keywords: 3t3 preadipocytes; sasp; senescence; epigallocatechin gallate ... See more keywords
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Cistanche promotes the adipogenesis of 3T3-L1 preadipocytes

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Published in 2022 at "PLoS ONE"

DOI: 10.1371/journal.pone.0264772

Abstract: Cistanche deserticola Ma (cistanche) is a traditional herb with a wide range of therapeutic properties. However, no evidence of cistanche’s effect on adipogenesis has been found. The effect of cistanche that promotes the adipogenesis of… read more here.

Keywords: cistanche; 3t3 preadipocytes; promotes adipogenesis; adipogenesis 3t3 ... See more keywords
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Simvastatin downregulates adipogenesis in 3T3-L1 preadipocytes and orbital fibroblasts from Graves’ ophthalmopathy patients

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Published in 2019 at "Endocrine Connections"

DOI: 10.1530/ec-19-0319

Abstract: Background Smoking is a strong risk factor for the development of Graves’ ophthalmopathy (GO). Immediate early genes (IEGs) are overexpressed in patients with active GO compared to healthy controls. The aim of this study was… read more here.

Keywords: expression; simvastatin; 3t3 preadipocytes; graves ophthalmopathy ... See more keywords
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FAM3A enhances adipogenesis of 3T3-L1 preadipocytes via activation of ATP-P2 receptor-Akt signaling pathway

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Published in 2017 at "Oncotarget"

DOI: 10.18632/oncotarget.17578

Abstract: FAM3A plays important roles in regulating hepatic glucose/lipid metabolism and the proliferation of VSMCs. This study determined the role and mechanism of FAM3A in the adipogenesis of 3T3-L1 preadipocytes. During the adipogenesis of 3T3-L1 preadipocytes,… read more here.

Keywords: fam3a expression; adipogenesis 3t3; 3t3 preadipocytes; fam3a enhances ... See more keywords