Articles with "3xtg mouse" as a keyword



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Altered slow (

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Published in 2019 at "Neurobiology of Aging"

DOI: 10.1016/j.neurobiolaging.2019.02.009

Abstract: The 3xTg-AD mouse model reproduces the main features associated with the etiology of familial Alzheimer's disease (AD). To investigate whether these features imply functional cortical network alterations and their evolution with age, we studied spontaneous… read more here.

Keywords: beta gamma; 3xtg mouse; alzheimer disease; mouse model ... See more keywords
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Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer’s Disease

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Published in 2021 at "Frontiers in Neuroscience"

DOI: 10.3389/fnins.2021.785276

Abstract: Animal models of disease are valuable resources for investigating pathogenic mechanisms and potential therapeutic interventions. However, for complex disorders such as Alzheimer’s disease (AD), the generation and availability of innumerous distinct animal models present unique… read more here.

Keywords: 3xtg mouse; characterization; model; alzheimer disease ... See more keywords