Preferential Solvation Study of the Synthesized Aldose Reductase Inhibitor (SE415) in the {PEG 400 (1) + Water (2)} Cosolvent Mixture and GastroPlus-Based Prediction
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DOI: 10.1021/acsomega.1c05788
Abstract: (Z)-N-Benzyl-2-{2,4-dioxo-5-(4-prop-2-yl-1-yloxyl)benzylidene)thiazolin-3-yl)}acetamide (SE415) is a novel aldose reductase inhibitor used in the management of diabetes mellitus (DM) and associated complications. Herein, the drug was solubilized (mole fraction solubility) in a “PEG 400 (polyethylene glycol 400) +… read more here.
Keywords: 400 water; preferential solvation; se415 peg; peg 400 ... See more keywords
An Efficient and Green Microwave-Assisted One Pot Synthesis of Imidazothiadiazoles in PEG-400 and Water
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DOI: 10.1080/10406638.2019.1695637
Abstract: Abstract Imidazothiadiazoles have attracted great deal of interest because of its several valuable diversified applications in the field of medicinal chemistry. Therefore, there is, requirement to design new environmentally benign protocol for the synthesis of… read more here.
Keywords: 400 water; efficient green; synthesis; one pot ... See more keywords
Acute effect of Clitoria ternatea flower beverage on glycemic response and antioxidant capacity in healthy subjects: a randomized crossover trial
Sign Up to like & getrecommendations! Published in 2018 at "BMC Complementary and Alternative Medicine"
DOI: 10.1186/s12906-017-2075-7
Abstract: BackgroundClitoria ternatea L., a natural food-colorant containing anthocyanin, demonstrated antioxidant and antihyperglycemic activity. The aim of this study was to determine the effects of Clitoria ternatea flower extract (CTE) on postprandial plasma glycemia response and… read more here.
Keywords: plasma; antioxidant capacity; capacity; 400 water ... See more keywords
Solubility and Thermodynamic Properties of Febuxostat in Various (PEG 400 + Water) Mixtures
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DOI: 10.3390/ma15207318
Abstract: The solubility of the poorly soluble medicine febuxostat (FXT) (3) in various {polyethylene glycol 400 (PEG 400) (1) + water (H2O) (2)} mixtures has been examined at 298.2–318.2 K and 101.1 kPa. FXT solubility was… read more here.
Keywords: 400 water; solubility; peg 400; h2o ... See more keywords