Progress Toward a Large-Scale Synthesis of Molnupiravir (MK-4482, EIDD-2801) from Cytidine
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DOI: 10.1021/acsomega.1c00772
Abstract: Molnupiravir (MK-4482, EIDD-2801) is a promising orally bioavailable drug candidate for the treatment of COVID-19. Herein, we describe a supply-centered and chromatography-free synthesis of molnupiravir from cytidine, consisting of two steps: a selective enzymatic acylation… read more here.
Keywords: molnupiravir 4482; molnupiravir; synthesis molnupiravir; 4482 eidd ... See more keywords