β4GalT1 Mediates PPARγ N-Glycosylation to Attenuate Microglia Inflammatory Activation
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DOI: 10.1007/s10753-018-0789-4
Abstract: The inflammatory activation of microglia has double-edged effects in central nervous system (CNS) diseases. The ligand-activated transcriptional factor peroxisome proliferator-activated receptor γ (PPARγ) inhibits the inflammatory response. β-1,4-Galactosyltransferase Ι (β1, 4GalT1) mediates N-glycosylation. In this… read more here.
Keywords: ppar; 4galt1 mediates; inflammatory activation; glycosylation ... See more keywords