Optimization of the precursor supply for an enhanced FK506 production in Streptomyces tsukubaensis
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DOI: 10.3389/fbioe.2022.1067467
Abstract: Tacrolimus (FK-506) is a macrolide widely used as immunosuppressant to prevent transplant rejection. Synthetic production of FK-506 is not efficient and costly, whereas the biosynthesis of FK-506 is complex and the level produced by the… read more here.
Keywords: supply; production; tsukubaensis; lysine ... See more keywords