Articles with "5083 resistant" as a keyword



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Sulforaphane is Synergistic with CB‐5083 and Inhibits Colony Formation of CB‐5083‐Resistant HCT116 Cells

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Published in 2022 at "ChemMedChem"

DOI: 10.1002/cmdc.202200030

Abstract: Human p97 is a potential drug target in oncology. Mutation‐driven drug resistance is an obstacle to the long‐term efficacy of targeted therapy. We found that the ATPase activity for one of the CB‐5083‐resistant p97 mutants… read more here.

Keywords: sulforaphane synergistic; 5083 resistant; 5083 inhibits; hct116 cells ... See more keywords