LC8/DYNLL1 is a 53BP1 effector and regulates checkpoint activation.
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DOI: 10.1093/nar/gkz263
Abstract: The tumor suppressor protein 53BP1 plays key roles in response to DNA double-strand breaks (DSBs) by serving as a master scaffold at the damaged chromatin. Current evidence indicates that 53BP1 assembles a cohort of DNA… read more here.
Keywords: 53bp1 effector; lc8; lc8 dynll1; checkpoint activation ... See more keywords