Ionizing Radiation-Induced DNA Damage Response in Primary Melanocytes and Keratinocytes of Human Skin
Sign Up to like & getrecommendations! Published in 2022 at "Cytogenetic and Genome Research"
DOI: 10.1159/000527037
Abstract: Currently, our knowledge of how different cell types in a tissue microenvironment respond to low and high linear energy transfer (LET) radiation is highly restricted. In this study, a comparative analysis was performed on γ-ray-induced… read more here.
Keywords: 53bp1 foci; melanocytes keratinocytes; ionizing radiation; dna damage ... See more keywords
Assessment of Individual Radiosensitivity in Breast Cancer Patients Using a Combination of Biomolecular Markers
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11041122
Abstract: About 5% of patients undergoing radiotherapy (RT) develop RT-related side effects. To assess individual radiosensitivity, we collected peripheral blood from breast cancer patients before, during and after the RT, and γH2AX/53BP1 foci, apoptosis, chromosomal aberrations… read more here.
Keywords: 53bp1 foci; cancer patients; breast cancer; h2ax 53bp1 ... See more keywords
Assessment of γ-H2AX and 53BP1 Foci in Peripheral Blood Lymphocytes to Predict Subclinical Hematotoxicity and Response in Somatostatin Receptor-Targeted Radionuclide Therapy for Advanced Gastroenteropancreatic Neuroendocrine Tumors
Sign Up to like & getrecommendations! Published in 2021 at "Cancers"
DOI: 10.3390/cancers13071516
Abstract: Simple Summary Assessment of the radiation-induced alterations in peripheral blood lymphocytes is a validated strategy for biological dosimetry and assessment of individual radiosensitivity. However, its clinical significance as a liquid biopsy for predicting hematotoxicity and… read more here.
Keywords: h2ax 53bp1; response; hematotoxicity; peripheral blood ... See more keywords