Articles with "54276 novel" as a keyword



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Abstract 463: GRC 54276, a novel small molecule inhibitor of HPK1 has entered phase 1/2 clinical trial insolid malignancies and Hodgkin’s/non Hodgkin’s lymphoma

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Published in 2023 at "Cancer Research"

DOI: 10.1158/1538-7445.am2023-463

Abstract: Background: Pre-clinical profile of GRC 54276, a clinical candidate with Phase 1/2 clinical trial ongoing, is presented here. GRC 54276 is a novel small molecule inhibitor of Hematopoietic progenitor kinase 1 (HPK1), a serine/threonine kinase1,2… read more here.

Keywords: 54276 novel; grc; hpk1; clinical trial ... See more keywords