Articles with "5hmc modified" as a keyword



A temperature-driven DNA discrimination strategy to distinguish E. coli DNA and phage 5hmC-modified DNA

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Published in 2025 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkaf501

Abstract: Abstract The arms race between phages and bacteria is dynamic and ongoing, with both continuously acquiring new strategies to outcompete each other during co-evolution. Here, we report bacteriophage T4 exonuclease DexA and an uncharacterized Escherichia… read more here.

Keywords: modified dna; 5hmc modified; phage; temperature driven ... See more keywords

Integrative Analysis of 5-Hydroxymethylcytosine and Transcriptional Profiling Identified 5hmC-Modified lncRNA Panel as Non-Invasive Biomarkers for Diagnosis and Prognosis of Pancreatic Cancer

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Published in 2022 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2022.845641

Abstract: Pancreatic adenocarcinoma (PAAD) is the fourth leading cause of cancer-related deaths worldwide. 5-Hydroxymethylcytosine (5hmC)-mediated epigenetic regulation has been reported to be involved in cancer pathobiology and has emerged to be promising biomarkers for cancer diagnosis… read more here.

Keywords: hydroxymethylcytosine; cancer; 5hmc modified; diagnosis prognosis ... See more keywords