5HT2A receptor blockade in dorsomedial striatum reduces repetitive behaviors in BTBR mice
Sign Up to like & getrecommendations! Published in 2017 at "Genes"
DOI: 10.1111/gbb.12343
Abstract: Restricted and repetitive behaviors are a defining feature of autism, which can be expressed as a cognitive flexibility deficit or stereotyped, motor behaviors. There is limited knowledge about the underlying neuropathophysiology contributing to these behaviors.… read more here.
Keywords: autism; 5ht2a receptor; dorsomedial striatum; receptor ... See more keywords
Hallucinogenic/psychedelic 5HT2A receptor agonists as rapid antidepressant therapeutics: Evidence and mechanisms of action
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Psychopharmacology"
DOI: 10.1177/0269881120986422
Abstract: Major depressive disorder (MDD) is among the most prevalent mental health disorders worldwide, and it is associated with a reduced quality of life and enormous costs to health care systems. Available drug treatments show low-to-moderate… read more here.
Keywords: hallucinogenic psychedelic; receptor agonists; evidence; psychedelic 5ht2a ... See more keywords