Abnormal [18F]NIFENE binding in transgenic 5xFAD mouse model of Alzheimer's disease: In vivo PET/CT imaging studies of α4β2* nicotinic acetylcholinergic receptors and in vitro correlations with Aβ plaques
Sign Up to like & getrecommendations! Published in 2023 at "Synapse"
DOI: 10.1002/syn.22265
Abstract: Since cholinergic dysfunction has been implicated in Alzheimer's disease (AD), the effects of Aβ plaques on nicotinic acetylcholine receptors (nAChRs) α4β2* subtype were studied using the transgenic 5xFAD mouse model of AD. Using the PET… read more here.
Keywords: 18f nifene; 5xfad mice; vivo pet; mice ... See more keywords
Adiponectin improves long-term potentiation in the 5XFAD mouse brain
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-45509-0
Abstract: Adiponectin is an adipokine that regulates apoptosis, glucose and lipid metabolism, and insulin sensitivity in metabolic diseases. As recent studies have associated changes in adipokines and other metabolites in the central nervous system with a… read more here.
Keywords: long term; term potentiation; 5xfad mouse;