Genome-wide RNAi screen identifies novel players in human 60S subunit biogenesis including key enzymes of polyamine metabolism
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DOI: 10.1093/nar/gkac072
Abstract: Abstract Ribosome assembly is an essential process that is linked to human congenital diseases and tumorigenesis. While great progress has been made in deciphering mechanisms governing ribosome biogenesis in eukaryotes, an inventory of factors that… read more here.
Keywords: 60s subunit; polyamine metabolism; wide rnai; enzymes polyamine ... See more keywords
Eukaryotic Ribosome Biogenesis: The 60S Subunit
Sign Up to like & getrecommendations! Published in 2022 at "Acta Naturae"
DOI: 10.32607/actanaturae.11541
Abstract: Ribosome biogenesis is consecutive coordinated maturation of ribosomal precursors in the nucleolus, nucleoplasm, and cytoplasm. The formation of mature ribosomal subunits involves hundreds of ribosomal biogenesis factors that ensure ribosomal RNA processing, tertiary structure, and… read more here.
Keywords: eukaryotic ribosome; 60s subunit; subunit eukaryotic; ribosome biogenesis ... See more keywords