[68Ga]Ga/[177Lu]Lu-BL01, a Novel Theranostic Pair for Targeting C-X-C Chemokine Receptor 4.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.9b00808
Abstract: C-X-C chemokine receptor type 4 (CXCR4) is overexpressed in hematological and solid malignancies. LY2510924 is a potent peptide antagonist of CXCR4. A derivative of LY2510924, BL01, was evaluated for theranostic applications targeting CXCR4. METHODS BL01… read more here.
Keywords: 177lu bl01; bl01; 68ga bl01; 68ga 177lu ... See more keywords
Potential airborne releases of theranostic radionuclides 68Ga and 177Lu: a method of preventive assessment of the radiological impact
Sign Up to like & getrecommendations! Published in 2025 at "Radiation Effects and Defects in Solids"
DOI: 10.1080/10420150.2025.2475382
Abstract: Introduction: The handling of radioactive solutions can lead to the production of airborne radioactivity which can potentially be released into the environment. To reduce this risk to a minimum, containment and protection systems are adopted.… read more here.
Keywords: method; method preventive; theranostic radionuclides; impact ... See more keywords
Development and Application of Radioactive Ligands Targeting Fibroblasts with Albumin-Binding Sites
Sign Up to like & getrecommendations! Published in 2025 at "Molecular Cancer Therapeutics"
DOI: 10.1158/1535-7163.mct-24-1108
Abstract: Abstract Fibroblast activation protein (FAP) is overexpressed on cancer-associated fibroblasts, making it an important target for cancer diagnosis and treatment, but limited tumor retention hinders late-stage diagnosis and radionuclide therapy. In this study, three albumin-bound… read more here.
Keywords: tumor; 177lu dota; 68ga 177lu; dota alb ... See more keywords
Novel NK1R-Targeted 68Ga-/177Lu-Radioconjugates with Potential Application against Glioblastoma Multiforme: Preliminary Exploration of Structure–Activity Relationships
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23031214
Abstract: Locoregionally administered, NK1 receptor (NK1R) targeted radionuclide therapy is a promising strategy for the treatment of glioblastoma multiforme. So far, the radiopharmaceuticals used in this approach have been based on the endogenous agonist of NK1R,… read more here.
Keywords: 177lu radioconjugates; glioblastoma multiforme; nk1r targeted; 68ga 177lu ... See more keywords
Preliminary Evaluation of Iron Oxide Nanoparticles Radiolabeled with 68Ga and 177Lu as Potential Theranostic Agents
Sign Up to like & getrecommendations! Published in 2022 at "Nanomaterials"
DOI: 10.3390/nano12142490
Abstract: Theranostic radioisotope pairs such as Gallium-68 (68Ga) for Positron Emission Tomography (PET) and Lutetium-177 (177Lu) for radioisotopic therapy, in conjunction with nanoparticles (NPs), are an emerging field in the treatment of cancer. The present work… read more here.
Keywords: 68ga 177lu; radiolabeled 68ga; 177lu mapeg; oxide nanoparticles ... See more keywords