68Ga-FAPI and 18F-FAPI PET/CT for detection of nodal metastases prior radical cystectomy in high-risk urothelial carcinoma patients
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-025-07239-6
Abstract: To determine the best therapeutic strategy for muscle-invasive bladder cancer (BC), the accuracy of lymph node staging is of paramount importance. However, diagnostic performance of conventional computed tomography in BC prior to radical cystectomy (RC)… read more here.
Keywords: fapi; 68ga fapi; lymph node; 18f fapi ... See more keywords
[68Ga]FAPI PET/CT reveals increased pulmonary fibroblast activation protein expression in long COVID patients after ICU discharge
Sign Up to like & getrecommendations! Published in 2025 at "European Journal of Nuclear Medicine and Molecular Imaging"
DOI: 10.1007/s00259-025-07376-y
Abstract: Post-acute sequelae of COVID-19 (PASC) has emerged as a major healthcare problem. A comprehensive mechanism of disease remains to be elucidated. In this study we aimed to explore pulmonary and muscle fibroblast activation protein (FAP)… read more here.
Keywords: covid patients; fibroblast activation; 68ga fapi; activation protein ... See more keywords
Synthesis and Preclinical Evaluation of a Novel FAPI-04 Dimer for Cancer Theranostics.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00965
Abstract: Overexpression of fibroblast activation protein (FAP) in cancer-associated fibroblasts in a wide variety of tumors enables a highly selective targeting strategy using FAP inhibitors (FAPIs). Quinoline-based FAPIs labeled with radionuclides have been widely developed for… read more here.
Keywords: fapi; novel fapi; fapi dimer; 68ga fapi ... See more keywords
Noninvasive Assessment of Renal Fibrosis of Chronic Kidney Disease in Rats by [68Ga]Ga-FAPI-04 Small Animal PET/CT and Biomarkers.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.3c00163
Abstract: Renal fibrosis is the most common pathological feature and common pathway of progression in chronic kidney disease (CKD). We evaluated [68Ga]Ga-FAPI-04 small animal positron emission tomography/computed tomography (PET/CT) and biomarkers as noninvasive assessments of renal… read more here.
Keywords: small animal; renal fibrosis; group; fapi small ... See more keywords
Radiolabeled Albumin Bound Fibroblast Activation Protein (FAP) Inhibitor-04 Enhances Precision in Renal Fibrosis Diagnosis via PET Imaging.
Sign Up to like & getrecommendations! Published in 2025 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.5c20457
Abstract: Renal fibrosis is a critical pathological feature of both acute kidney injury (AKI) and chronic kidney disease (CKD), yet noninvasive methods for early detection remain limited. Current imaging tracers, such as 18F-FDG and 68Ga-FAPI-04, suffer… read more here.
Keywords: pet imaging; fibrosis; renal fibrosis; fap inhibitor ... See more keywords
Valvular and myocardial fibroblast activation in aortic stenosis: a prospective positron emission tomography study
Sign Up to like & getrecommendations! Published in 2024 at "European Heart Journal"
DOI: 10.1093/eurheartj/ehae666.285
Abstract: In patients with aortic stenosis, fibrosis is a common pathophysiological feature of leaflet thickening as well as left ventricular decompensation as it transitions from hypertrophy to heart failure. Valvular fibrosis can be quantified by contrast-enhanced… read more here.
Keywords: fibrosis; patients aortic; stenosis; tomography ... See more keywords
NIMG-10. THE ROLE OF FIBROBLAST ACTIVATION PROTEIN IN GLIOBLASTOMA AND GLIOSARCOMA – A COMPARISON OF TISSUE, 68GA-FAPI-46 POSITRON EMISSION TOMOGRAPHY AND SURVIVAL DATA
Sign Up to like & getrecommendations! Published in 2024 at "Neuro-Oncology"
DOI: 10.1093/neuonc/noae165.0776
Abstract: Despite their unique histological features,gliosarcomas belong to the group of glioblastomas and are treated according to the same standards. Fibroblast-activation-protein(FAP) is a component of a tumor-specific subpopulation of fibroblasts that play a critical role in… read more here.
Keywords: fap expression; gliosarcoma; tumor; expression ... See more keywords
Using 18F-flurodeoxyglucose and 68Ga-fibroblast activation protein inhibitor PET/CT to evaluate a new periprosthetic joint infection model of rabbit due to Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2022 at "Nuclear Medicine Communications"
DOI: 10.1097/mnm.0000000000001495
Abstract: Supplemental Digital Content is available in the text. Purpose The existing periprosthetic joint infection (PJI) models have obvious limitations, and studies of PJI on animal models using PET/computed tomography (CT) for diagnosis are still lacking.… read more here.
Keywords: periprosthetic joint; joint infection; 18f fdg; model ... See more keywords
Elevated 68Ga-FAPI Activity in Splenic Hemangioma and Pneumonia.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000003638
Abstract: ABSTRACT A 59-year-old woman with newly diagnosed pulmonary nodules underwent both 18F-FDG and 68Ga-FAPI PET/CT. Both studies showed similarly increased uptake in pneumonia. However, only 68Ga-FAPI PET/CT showed increased uptake in splenic hemangioma, whereas FDG… read more here.
Keywords: fapi activity; splenic hemangioma; 68ga fapi; pneumonia ... See more keywords
Chronic Colitis Mimicking Malignancy on 68Ga-FAPI PET/CT.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000003793
Abstract: ABSTRACT A 40-year-old man presented with abdominal pain and diarrhea for 2 months. Abdominal CT showed thickening of the cecal wall, which was considered likely malignant. The patient was subsequently enrolled in a clinical trial… read more here.
Keywords: fapi pet; chronic colitis; 68ga fapi; malignancy ... See more keywords
18F-FDG PET/CT and 68Ga-FAPI-4 PET/CT Findings of Bilateral Knee Osteoarthritis in a Patient With Uveal Malignant Melanoma.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000003854
Abstract: ABSTRACT We present the findings of 68Ga-FAPI-4 PET/CT and 18F-FDG PET/CT of a metastatic malignant melanoma patient with osteoarthritis. A 65-year-old woman with a history of metastatic uveal malignant melanoma was referred to 18F-FDG PET/CT… read more here.
Keywords: malignant melanoma; 18f fdg; fdg pet; 68ga fapi ... See more keywords