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Published in 2018 at "Molecular Imaging and Biology"
DOI: 10.1007/s11307-018-1207-x
Abstract: PurposeIn recent years, considerable progress has been made in the use of gallium-68 labeled receptor-specific peptides for imaging oncologic diseases. The objective was to examine the stability and pharmacokinetics of [68Ga]NODAGA and DOTA-peptide conjugate targeting…
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Keywords:
peptide;
plasma urine;
nodaga peptide;
dota peptide ... See more keywords
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Published in 2022 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.2c00272
Abstract: As angiogenesis plays a key role in tumor growth and metastasis, the angiogenic process has attracted scientific interest as a target for diagnostic and therapeutic agents. Factors influencing angiogenesis include the vascular endothelial growth factor…
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Keywords:
68ga labeled;
growth;
68ga nodaga;
peptide ... See more keywords
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Published in 2021 at "Clinical nuclear medicine"
DOI: 10.1097/rlu.0000000000003732
Abstract: ABSTRACT A 52-year-old man with newly diagnosed gastric neuroendocrine tumor (NET) underwent 68Ga-NODAGA-JR11 and 68Ga-DOTATATE imaging. 68Ga-DOTATATE PET/CT showed no 68Ga-DOTATATE uptake in the lesion, where 68Ga-NODAGA-JR11 showed intense uptake. The patient subsequently received endoscopic…
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Keywords:
68ga dotatate;
68ga nodaga;
pet;
nodaga jr11 ... See more keywords
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Published in 2017 at "EJNMMI Research"
DOI: 10.1186/s13550-017-0288-x
Abstract: BackgroundIntegrin-targeting radiopharmaceuticals have potential broad applications, spanning from cancer theranostics to cardiovascular diseases. We have previously reported preclinical dosimetry results of 68Ga-NODAGA-RGDyK in mice. This study presents the first human dosimetry of 68Ga-NODAGA-RGDyK in the…
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Keywords:
nodaga rgdyk;
dosimetry;
first human;
dosimetry 68ga ... See more keywords
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Published in 2021 at "Diagnostics"
DOI: 10.3390/diagnostics11101807
Abstract: Angiogenesis is crucial in tissue repair and prevents scar tissue formation following an ischemic event such as myocardial infarction. The ischemia induces formation of new capillaries, which have high expression of integrin αvβ3. [68Ga]Ga-NODAGA-E[(cRGDyK)]2 ([68Ga]Ga-RGD)…
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Keywords:
angiogenesis;
myocardial infarction;
infarction;
nodaga crgdyk ... See more keywords
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Published in 2022 at "Molecules"
DOI: 10.3390/molecules27020543
Abstract: Background: Glucagon-like peptide 1 receptor (GLP-1R) is preferentially expressed in pancreatic islets, especially in β-cells, and highly expressed in human insulinomas and gastrinomas. In recent years several GLP-1R–avid radioligands have been developed to image insulin-secreting…
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Keywords:
68ga nodaga;
hplc method;
purity 68ga;
nodaga exendin ... See more keywords
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Published in 2022 at "Journal of Medical Physics"
DOI: 10.4103/jmp.jmp_34_22
Abstract: Aims: Calculation of the absorbed dose in human organs is one of the first steps for developing new radiopharmaceuticals. The aim of this study is to estimate the human absorbed dose of a newly developed…
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Keywords:
68ga nodaga;
rgd bbn;
dose assessment;
nodaga rgd ... See more keywords