Structural Basis for Activation of the Heterodimeric GABAB Receptor.
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DOI: 10.1016/j.jmb.2020.09.023
Abstract: The neurotransmitter γ-aminobutyric acid (GABA) activates the metabotropic GABAB receptor to generate slow, prolonged inhibitory signals that regulate the neural circuitry. The GABAB receptor is an obligate heterodimeric G protein-coupled receptor (GPCR) comprised of GBR1… read more here.
Keywords: receptor; 7tm domain; activation; gabab receptor ... See more keywords