Structure of Gcn1 bound to stalled and colliding 80S ribosomes
Sign Up to like & getrecommendations! Published in 2021 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2022756118
Abstract: Significance There is growing evidence that collisions between ribosomes represent a cellular signal for activating multiple stress pathways, such as ribosome-associated quality control (RQC), the ribotoxic stress response, and the integrated stress response (ISR). Here… read more here.
Keywords: protein; isr; microscopy; site ... See more keywords
Structural rearrangements in mRNA upon its binding to human 80S ribosomes revealed by EPR spectroscopy
Sign Up to like & getrecommendations! Published in 2018 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkx1136
Abstract: Abstract The model mRNA (MR), 11-mer RNA containing two nitroxide spin labels at the 5′- and 3′-terminal nucleotides and prone to form a stable homodimer (MR)2, was used for Electron Paramagnetic Resonance study of structural… read more here.
Keywords: rearrangements mrna; upon binding; structural rearrangements; binding human ... See more keywords