888-P: Targeting Toxic Human IAPP Aggregation in Type 2 Diabetes Development with Antimicrobial Peptides
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DOI: 10.2337/db25-888-p
Abstract: Introduction and Objective: Human islet amyloid polypeptide (hIAPP) is a pancreatic β-cell neuropeptide hormone co-secreted with insulin. However, it is also amyloidogenic. The hypersecretion of hIAPP in pre-diabetes is hypothesised to induce its aggregation, which… read more here.
Keywords: hiapp; hiapp aggregation; amp; 888 targeting ... See more keywords