Abstract 3028: PET imaging with the bispecific 89Zr-antibody ERY974 targeting CD3 and glypican 3 in tumor-bearing mouse models
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DOI: 10.1158/1538-7445.am2018-3028
Abstract: BACKGROUND: ERY974, a modified monoclonal IgG4 bispecific antibody directed against human CD3 on T cells and glypican 3 (GPC3) on tumor cell, is currently in phase I clinical trial. The oncofetal protein GPC3 is overexpressed… read more here.
Keywords: mouse models; pet; 89zr ery974; tumor uptake ... See more keywords